Eur Heart J ; 4:H Gresser U, Gleiter CH. Erectile dysfunction: comparison of efficacy and side effects of the PDE-5 inhibitors sildenafil, vardenafil and tadalafil. Review of literature. Eur J Med ; Erectile dysfunction and the cardiovascular patients: endothelial dysfunction is the common denominator.
Heart ; Lundbeck Takeda Pharmaceuticals U. Cialis tadalafil Profile. Profile Contact Information. Currently Enrolling Trials Show More. Chemists at the Pfizer pharmaceutical company found, however, that while the drug had little effect on angina, it could induce penile erections, typically within 30 to 60 minutes.
Seeing the economic opportunity in such a biochemical effect, Pfizer decided to market the drug for impotence. Though unconfirmed, it is believed the drug was invented by Peter Dunn and Albert Wood. Though available by prescription only, Viagra was marketed on television, famously touted by ex-presidential candidate Bob Dole , then in his mids.
An estimated 30 million men in the United States suffer from erectile dysfunction and a wave of new Viagra competitors, among them Cialis tadalafil and Levitra vardenafil , has blown open the market. Drug companies are now not just targeting older men like Dole, but men in their 30s and 40s, too.
But if you see something that doesn't look right, click here to contact us! Khrushchev, born into a Ukrainian peasant family in , worked as a mine In Washington, D. The event was held in celebration of a gift, by the The strongest earthquake in American history, measuring 9. Some people were killed and thousands injured. The massive earthquake had its epicenter about 12 miles north of Prince William Sound.
The active ingredient can remain longer if you have problems with your kidneys or liver, or you are taking certain other medications. Stop sexual activity and get medical help right away if you get symptoms such as chest pain, dizziness, or nausea during sex. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease. Ask your healthcare provider if your heart is healthy enough for you to have sexual activity.
You should not take CIALIS if your healthcare provider has told you not to have sexual activity because of your health problems. Before taking CIALIS, tell your healthcare provider about all your medical problems, particularly if you have or ever had:. Tell your healthcare provider about all the medicines you take especially if you take:. The most common side effects with CIALIS are: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose.
These side effects usually go away after a few hours. Back pain and muscle aches usually go away within 2 days. Call your healthcare provider if you get any side effect that bothers you or one that does not go away. Uncommon but serious side effects include: An erection that won't go away: If you get an erection lasting more than 4 hours, seek immediate medical help to avoid long-term injury.
In rare instances, men taking prescription ED tablets, including CIALIS, reported a sudden decrease or loss of vision or hearing sometimes with ringing in the ears and dizziness. It's not possible to determine if these events are related directly to the ED tablets or to other factors.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www. The maker of this brand is not affiliated with and does not endorse Eli Lilly and Company or its products. About Eli Lilly and Company Lilly, a leading innovation-driven corporation, is developing a growing portfolio of pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations.
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